Soal immunology, in English euyyyy ^,^ (minggu1)

Source: Pathophysiology,PreTest,Self-Assessment and Review

Second Edition

By : Maurice A. Mufson, M.D., M.A.C.P.

Immune System

Questions

 

DIRECTIONS: Each item below contains a question or incomplete

statement followed by suggested responses. Select the one best response to

each question.

 

1. The major immunoglobulin class in normal adult human serum is

a. IgA

b. IgG

c. IgM

d. IgE

e. IgD

 

2. The predominant antibody found in a primary immune response is

a. IgA

b. IgG

c. IgM

d. IgE

e. IgD

 

3. Which immunoglobulin class is found on the surface of mast cells?

a. IgA

b. IgG

c. IgM

d. IgE

e. IgD

 

4. Which immunoglobulin class is a major component of mucosal secretions?

a. IgA

b. IgG

c. IgM

d. IgE

e. IgD

 

5. Which immunoglobulin class can cross the placenta?

a. IgA

b. IgG

c. IgM

d. IgE

e. IgD

 

6. Which of the following cells are important in an innate immune

response to extracellular bacteria?

a. T lymphocytes

b. B lymphocytes

c. Neutrophils

d. Eosinophils

e. Mast cells

 

7. Which one of the following is the most potent and effective antigenpresenting

cell (APC)?

a. Monocytes-macrophages

b. Mast cells

c. T lymphocytes

d. B lymphocytes

e. Dendritic-Langerhans cells

 

8. Compared with a healthy individual, lymph nodes from a person with

a deficiency in B lymphocytes would have

a. Few or no primary follicles

b. Enlarged germinal centers

c. Few Howell-Jolly bodies

d. No paracortex

e. Increased number of Heinz bodies

 

9. A newborn infected with group B streptococcus would produce and

secrete antibody of which of the following class(es)?

a. IgM only

b. IgG only

c. IgM and IgG

d. Neither IgM nor IgG

e. IgA only

10. Eosinophils are associated with the defense against infections caused by

a. Virus

b. Intracellular bacteria

c. Extracellular bacteria

d. Invasive parasites

e. Mycoplasma

 

11. To determine whether a fetus acquired an infection in utero, antigenspecific

antibody to which of the following classes should be measured?

a. IgA

b. IgM

c. IgG

d. IgD

e. IgE

 

12. During an immune response, antibodies are made against different

structures (usually proteins) on an infectious agent. These structures are

referred to as

a. Adjuvants

b. Allotypes

c. Isotypes

d. Epitopes

e. Alleles

 

13. Which one of the following complement components enhances

phagocytosis of bacteria by opsonization?

a. C1

b. Factor B

c. C3b

d. C5a

e. C5b6789

 

14. Which one of the following complement components mediates cytolysis?

a. C1

b. Factor B

c. C3b

d. C5a

e. C5b6789

 

15. Which one of the following complement components is a chemoattractant

for neutrophils?

a. C1

b. Factor B

c. C3b

d. C5a

e. C5b6789

 

16. Which one of the following complement components binds to antibody

to activate the classical pathway?

a. C1

b. Factor B

c. C3b

d. C5a

e. C5b6789

 

17. A patient with a predisposition for disseminated infections by Neisseria

bacteria may have a deficiency in

a. Membrane attack complex formation (C5 to C9)

b. Classical pathway activation

c. C3

d. C1 inhibitor

e. C4

 

18. Which one of the following complement component deficiencies is

associated with individuals with frequent pyogenic bacterial infections?

a. Membrane attack complex (C5 to C9)

b. C1 inhibitor

c. C2

d. C3

e. C4

 

19. A person with an abnormality in which one of the following early

complement components would most likely experience the most serious

clinical manifestations?

a. C1

b. C2

c. C3

d. Factor B

e. C1 inhibitor

20. A 6-year-old boy has received a deep puncture wound while playing

in his neighbor's yard. His records indicate that he has had the standard

DPT immunizations and a booster when he entered school. What is the

most appropriate therapy for this child?

a. Tetanus toxoid

b. Tetanus antitoxin

c. Both toxoid and antitoxin at the same site

d. Toxoid and antitoxin at different sites

e. No treatment

 

21. Toxic shock syndrome toxin-1 is produced by some strains of S. aureus

and is thought to be responsible for the clinical manifestations of disease by

this organism. This toxin is referred to as a superantigen because it can

a. Activate T cells in an antigen-nonspecific manner

b. Activate B cells without T cell help

c. Become immunogenic when attached to a carrier protein

d. Prolong the presence of antigen in a tissue

e. Evoke IgE

 

22. Neutralizing antiviral antibody produced in response to infection by

an enveloped virus acts on which one of the following components of the

virus?

a. Matrix proteins

b. One or more surface glycoproteins

c. Internal protein components

d. Nucleic acid

e. Internal nonprotein components

 

23. Direct killing of cells infected with virus is usually accomplished by

a. CD8-positive T cells

b. CD4-positive T helper 1 cells

c. CD4-positive T helper 2 cells

d. plasma cells

e. CD19-positive B cells

24. Mycobacterium tuberculosis results in an intracellular bacterial infection

that provokes which one of the following immune responses?

a. Natural killer cytotoxic response

b. CD8-positive cytotoxic T cell response

c. T helper 1 delayed type hypersensitivity response

d. Complement mediated lysis of infected cell

e. Eosinophilia

 

25. Which one of the following is a B cell neoplasm?

a. Non-Hodgkin's lymphoma

b. Acute lymphoblastic leukemia

c. Burkitt's lymphoma

d. Hodgkin's disease

e. Histiocytosis X

 

26. During an immune response to pathogens in the intestine, the primary

function of M cells along the Peyer's patches is to

a. Transport antigen to lymphocytes

b. Produce antigen-specific IgA antibody

c. Present antigen to lymphocytes

d. Secrete cytokines to "help" in antibody production

e. Secrete chemokines

 

27. Which one of the following tests is used for the determination of the

titer of antihepatitis B antibody?

a. Flow cytometry (FACS)

b. Enzyme-linked immunosorbent assay (ELISA)

c. Latex agglutination

d. Coombs' test

e. Mixed lymphocyte reaction

 

28. Which one of the following tests is used for the detection of anti-Rh

antibody in blood?

a. Flow cytometry (FACS)

b. Enzyme-linked immunosorbent assay (ELISA)

c. Latex agglutination

d. Coombs' test

e. Mixed lymphocyte reaction

29. Which one of the following tests is used for the assessment of the level

of CD4T lymphocytes in an HIV-infected patient?

a. Flow cytometry (FACS)

b. Enzyme-linked immunosorbent assay (ELISA)

c. Latex agglutination

d. Coombs' test

e. Mixed lymphocyte reaction

 

30. Which one of the following tests is used for the evaluating the degree

of compatibility between donor and patient lymphocytes?

a. Flow cytometry (FACS)

b. Enzyme-linked immunosorbent assay (ELISA)

c. Latex agglutination

d. Coombs' test

e. Mixed lymphocyte reaction

 

31. Which one of the following tests is used for the detection of group A

streptococci from a throat swab?

a. Flow cytometry (FACS)

b. Enzyme-linked immunosorbent assay (ELISA)

c. Latex agglutination

d. Coombs' test

e. Mixed lymphocyte reaction

 

41. Which cytokine promotes the proliferation of T and B lymphocytes?

a. IFN-(interferon )

b. IL-2 (interleukin 2)

c. IL-4 (interleukin 4)

d. TNF-(tumor necrosis factor )

e. TGF-(transforming growth factor )

 

42. Which cytokine promotes various biologic actions associated with

inflammation?

a. IFN-(interferon )

b. IL-2 (interleukin 2)

c. IL-4 (interleukin 4)

d. TNF-(tumor necrosis factor )

e. TGF-(transforming growth factor )

 

43. Which cytokine antagonizes or suppresses many responses of lymphocytes?

a. IFN-(interferon )

b. IL-2 (interleukin 2)

c. IL-4 (interleukin 4)

d. TNF-(tumor necrosis factor )

e. TGF-(transforming growth factor )

44. Which cytokine functions as a promotor of T helper 2 (TH2) development

and IgE synthesis?

a. IFN-(interferon )

b. IL-2 (interleukin 2)

c. IL-4 (interleukin 4)

d. TNF-(tumor necrosis factor )

e. TGF-(transforming growth factor )

 

45. Which cytokine functions as an activator of macrophages and natural

killer (NK) cells?

a. IFN-(interferon )

b. IL-2 (interleukin 2)

c. IL-4 (interleukin 4)

d. TNF-(tumor necrosis factor )

e. TGF-(transforming growth factor )

 

hohoho..pusing ya pake bahasa inggris, itulah kawan… c ndak lo sempat mentranslatenyo doh..(gayya lai, bantuak bisa lo baso inggirih..wekekeke)

bisa se beko tu..bisa..bisa…, kawan2 kan calon2 dokter yang akan bersaing samo dokter luar negri tu, jadi… biasakan pake bhs inggris lai,

' biasakan kebiasaan oleh orang yang biasa membiasakan kebiasaan yang biasa dibiasakannya itu..'

 

Ps: jawabannya nyusul y